Description

4-(Trifluoromethyl)-1,2-Dihydropyridazine-3,6-Dione is a high-value, fluorinated heterocyclic building block with the CAS number 1154868-54-8. This compound is critical for medicinal chemistry research and development, offering a unique trifluoromethylated dihydropyridazine-dione scaffold that can significantly influence the pharmacokinetic and metabolic properties of drug candidates. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring fluorinated components.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	4-(Trifluoromethyl)-1,2-Dihydropyridazine-3,6-Dione
CAS No.	1154868-54-8
Molecular Formula	C6H3F3N2O2
Molecular Weight	192.10 g/mol
Synonyms	4-(Trifluoromethyl)-1,2-dihydro-3,6-pyridazinedione; 4-(Trifluoromethyl)-1,2-dihydropyridazine-3,6-dione; 3,6-Dihydroxy-4-(trifluoromethyl)pyridazine; 1,2-Dihydro-4-(trifluoromethyl)pyridazine-3,6-dione; 4-Trifluoromethyl-1,2-dihydropyridazine-3,6-dione; 1154868-54-8; 4-(Trifluoromethyl)-1,6-dihydro-3H-pyridazine-3,6-dione
EINECS	Contact for details

Quality Control

Our production of 4-(Trifluoromethyl)-1,2-Dihydropyridazine-3,6-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.