Description

2,3-Difluoro-4-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly in the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing difluorinated biphenyl or terphenyl scaffolds.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluoro-isopropoxy phenyl moiety imparts specific biological activity and stability.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2,3-Difluoro-4-Isopropoxyphenylboronic Acid
CAS No.	1154762-01-2
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,3-Difluoro-4-isopropoxyphenyl)boronic acid; 2,3-Difluoro-4-(1-methylethoxy)benzeneboronic acid; 4-Isopropoxy-2,3-difluorophenylboronic acid; B-(2,3-Difluoro-4-isopropoxyphenyl)boronic acid; 2,3-Difluoro-4-propan-2-yloxybenzeneboronic acid; 1154762-01-2; DFIPA Boronic Acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), 11B/19F NMR conformity, and residual solvent content are available upon request. We adhere to cGMP principles for production where applicable to support our customers in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (1H, 11B, 19F)
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.