Description

2,2-Dimethyl-5-[(2,4,5-Trifluorophenyl)Acetyl]-1,3-Dioxane-4,6-Dione is a high-value, specialized organic intermediate featuring a unique dioxanedione core functionalized with a trifluorophenylacetyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical sector where its structure enables the introduction of specific fluorinated motifs. It is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethylphenyl moiety.
• Fluorinated Compound Research: Serves as a versatile scaffold for introducing fluorine atoms into complex molecular architectures in medicinal and material chemistry.
• Chemical Development: Employed in process chemistry for scale-up and optimization of synthetic routes involving sensitive dione chemistry.
• Academic & R&D: A valuable reagent for universities and corporate R&D labs exploring new reactions and catalytic processes with fluorinated building blocks.

Basic Information

Item	Detail
Product Name	2,2-Dimethyl-5-[(2,4,5-Trifluorophenyl)Acetyl]-1,3-Dioxane-4,6-Dione
CAS No.	1152439-73-0
Molecular Formula	C14H11F3O5
Molecular Weight	316.23 g/mol
Synonyms	5-(2,4,5-Trifluorophenylacetyl)-2,2-dimethyl-1,3-dioxane-4,6-dione; 2,2-Dimethyl-5-(2,4,5-trifluorophenylacetyl)-1,3-dioxane-4,6-dione; Meldrum's acid derivative, trifluorophenylacetyl-; 1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[(2,4,5-trifluorophenyl)acetyl]-; Trifluorophenylacetyl Meldrum's acid derivative
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-5-[(2,4,5-Trifluorophenyl)Acetyl]-1,3-Dioxane-4,6-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.