Description

Potassium 2-Fluoro-4-(Trifluoromethyl)Phenyltrifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. This compound is valued for its role in facilitating efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, due to its enhanced stability and reactivity profile compared to traditional boronic acids. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for constructing complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and fluoro substituents for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Material Science: Serves as a building block for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant boron reagent for forming carbon-carbon bonds between aromatic rings.
• Chemical Research & Development: A valuable tool for medicinal and process chemists exploring new chemical entities and optimizing synthetic routes.
• Fluorine Chemistry: Integral to the development of new fluorination methodologies and the study of structure-activity relationships in fluorinated compounds.

Basic Information

Product Name	Potassium 2-Fluoro-4-(Trifluoromethyl)Phenyltrifluoroborate
CAS No.	1150655-12-1
Molecular Formula	C7H3BF7K
Molecular Weight	281.99 g/mol
Synonyms	Potassium (2-Fluoro-4-(trifluoromethyl)phenyl)trifluoroborate; Potassium 2-Fluoro-α,α,α-trifluoro-p-tolyltrifluoroborate; 2-Fluoro-4-(trifluoromethyl)phenyltrifluoroborate Potassium Salt; (2-Fluoro-4-(trifluoromethyl)phenyl)trifluoroboronic Acid Potassium Salt; Potassium Trifluoro(2-fluoro-4-(trifluoromethyl)phenyl)borate; B-(2-Fluoro-4-(trifluoromethyl)phenyl)trifluoroboronic Acid Potassium Salt; Potassium Organotrifluoroborate Salt (2-Fluoro-4-(trifluoromethyl)phenyl); K-2F-4-TFM-Phenyl-TFB
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by NMR or HPLC), residual solvent content, and moisture levels (Karl Fischer) are available upon request. We adhere to strict quality management protocols to ensure supply reliability and product performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (NMR)	≥95%
Purity (HPLC)	≥97%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.