Description

2-Fluoro-4,5-Dimethylphenylboronic Acid, Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is essential as a key building block in modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block for creating fluorinated and dimethyl-substituted biaryl scaffolds found in drug candidates.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science & OLED Development: Incorporated into the synthesis of organic semiconductors, liquid crystals, and light-emitting materials.
• Chemical Biology & Probe Development: Employed to create tagged molecules for studying biological processes and target engagement.
• Scale-up Process Chemistry: The pinacol ester offers enhanced stability, making it suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	2-Fluoro-4,5-Dimethylphenylboronic Acid, Pinacol Ester
CAS No.	1150271-75-2
Molecular Formula	C14H20BFO2
Molecular Weight	250.12 g/mol
Synonyms	2-Fluoro-4,5-dimethylbenzeneboronic acid pinacol ester; (2-Fluoro-4,5-dimethylphenyl)boronic acid pinacol ester; 4,5-Dimethyl-2-fluorophenylboronic acid pinacol ester; Pinacol (2-fluoro-4,5-dimethylphenyl)boronate; 2-Fluoro-4,5-dimethylphenyl-B(pin); B-(2-Fluoro-4,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4,5-Dimethylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.