Description

2-(4-Bromo-2-Fluoro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly in the development of new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create complex aryl-aryl bonds in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for diagnostic and research applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale synthesis due to its stability and reactivity profile.

Basic Information

Product Name	2-(4-Bromo-2-Fluoro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1150271-71-8
Molecular Formula	C13H17BBrFO3
Molecular Weight	330.99 g/mol
Synonyms	4-Bromo-2-fluoro-5-methoxyphenylboronic acid pinacol ester; (4-Bromo-2-fluoro-5-methoxyphenyl)boronic acid pinacol ester; 2-Fluoro-4-bromo-5-methoxyphenylboronic acid pinacol ester; 1150271-71-8; 4-Bromo-2-fluoro-5-methoxybenzeneboronic acid pinacol ester; Pinacol (4-bromo-2-fluoro-5-methoxyphenyl)boronate; 2-(4-Bromo-2-fluoro-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-2-Fluoro-5-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept in a well-ventilated area, away from heat and incompatible materials. Due to its hygroscopic and light-sensitive nature, allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.