Description

2-Acetamido-4-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound that serves as a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected aniline moiety, enabling precise molecular construction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who are developing novel active ingredients, particularly those targeting complex trifluoromethyl-substituted aromatic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing the pharmacologically important trifluoromethyl group.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides where the phenylboronic acid moiety facilitates structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: A pivotal reagent for forming carbon-carbon bonds in the synthesis of complex, biaryl-structured compounds under mild conditions.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-Acetamido-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1150271-57-0
Molecular Formula	C9H9BF3NO3
Molecular Weight	247.98 g/mol
Synonyms	[2-Acetamido-4-(trifluoromethyl)phenyl]boronic acid; 2-Acetamido-4-(trifluoromethyl)benzeneboronic acid; N-[4-(Trifluoromethyl)-2-boronophenyl]acetamide; B-[2-Acetamido-4-(trifluoromethyl)phenyl]boronic acid; 2-Acetylamino-4-trifluoromethylphenylboronic acid; 2-Acetamido-α,α,α-trifluoro-p-tolylboronic acid; (2-Acetamido-4-(trifluoromethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Acetamido-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.