Description

2-Acetamido-5-Fluorophenylboronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its value lies in its role as a protected boronic acid derivative, offering enhanced stability and solubility for demanding cross-coupling reactions, particularly in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in drug discovery pipelines.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex molecules with potential therapeutic applications.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and probe development.
• Academic & Contract Research: A valuable tool for methodological development and library synthesis in research laboratories.

Basic Information

Product Name	2-Acetamido-5-Fluorophenylboronic Acid, Pinacol Ester
CAS No.	1150271-55-8
Molecular Formula	C14H19BFNO3
Molecular Weight	279.12 g/mol
Synonyms	5-Fluoro-2-acetamidophenylboronic acid pinacol ester; N-[5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide; 2-Acetamido-5-fluorobenzeneboronic acid pinacol ester; (2-Acetamido-5-fluorophenyl)boronic acid pinacol ester; 5-Fluoro-2-(N-acetylamino)phenylboronic acid pinacol ester; Boronic acid, B-[2-(acetylamino)-5-fluorophenyl]-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our 2-Acetamido-5-Fluorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.