Description

2-Fluoro-5-Pentanoylphenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group for Suzuki-Miyaura cross-coupling reactions with a ketone moiety for further derivatization. This compound is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in constructing complex molecular scaffolds for novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or building block for creating advanced organic materials and polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Fluoro-5-Pentanoylphenylboronic Acid, Pinacol Ester
CAS No.	1150271-37-6
Molecular Formula	C₁₇H₂₄BFO₃
Molecular Weight	306.18 g/mol
Synonyms	5'-Fluoro-2'-pentanoyl-[1,1'-biphenyl]-2-ylboronic acid pinacol ester; 2-Fluoro-5-(1-oxopentyl)phenylboronic acid pinacol ester; (2-Fluoro-5-pentanoylphenyl)boronic acid pinacol ester; 2-(5-Fluoro-2-pentanoylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Fluoro-2-pentanoylphenylboronic acid pinacol ester; 2-Fluoro-5-valerylphenylboronic acid pinacol ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our 2-Fluoro-5-Pentanoylphenylboronic Acid, Pinacol Ester is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive analytical data including HPLC purity, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and mass spectrometry for full structural confirmation. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.