Description

2-Cyano-4-Fluoro-1,3-Phenylenediboronic Acid is a high-purity, multi-functional boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated and cyano-substituted biaryl compounds, which are core structures in many drug candidates.
• Agrochemical Research: Used to create novel herbicide and pesticide molecules, leveraging the fluorine and cyano groups for enhanced biological activity and environmental stability.
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its boronic acid groups facilitate polymerization and conjugation.
• Chemical Synthesis: Versatile reagent for constructing complex organic molecules in academic and industrial R&D laboratories, particularly for introducing aromatic rings with specific functional handles.
• Ligand & Catalyst Development: Potential precursor for creating novel bidentate ligands used in transition metal catalysis.

Basic Information

Product Name	2-Cyano-4-Fluoro-1,3-Phenylenediboronic Acid
CAS No.	1150271-28-5
Molecular Formula	C8H6BF2NO4
Molecular Weight	224.95 g/mol
Synonyms	4-Fluoro-2-cyano-1,3-phenylenebis(boronic acid); 2-Cyano-4-fluoro-1,3-benzenediboronic acid; 1,3-Diboronic acid-2-cyano-4-fluorobenzene; 4-Fluoro-2-cyanobenzene-1,3-diboronic acid; 2-Cyano-4-fluorobenzene-1,3-diyldiboronic acid; 1150271-28-5; 4-Fluoro-2-cyanobenzene-1,3-diylbis(boronic acid)
EINECS	Contact for details

Quality Control

Our 2-Cyano-4-Fluoro-1,3-Phenylenediboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.