Description

4-Cyano-2-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, including herbicides and fungicides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing cyano and fluorine groups.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of boronic acid-based sensors and probes for detecting biological analytes like sugars and peroxides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific aryl boronic acid derivatives.

Basic Information

Product Name	4-Cyano-2-Fluorophenylboronic Acid
CAS No.	1150114-77-4
Molecular Formula	C7H5BFNO2
Molecular Weight	164.93 g/mol
Synonyms	(4-Cyano-2-fluorophenyl)boronic acid; 2-Fluoro-4-cyanophenylboronic acid; B-(4-Cyano-2-fluorophenyl)boronic acid; 4-Cyano-2-fluorobenzeneboronic acid; 1150114-77-4; 2-Fluoro-4-cyanobenzene-1-boronic acid; Boronic acid, B-(4-cyano-2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Cyano-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.