Description

3,5-Difluoro-2-Nitrophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to create novel herbicides and fungicides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a building block for creating specialized ligands and catalysts used in asymmetric synthesis and polymerization processes.
• Functional Material Research: Incorporated into the design of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	3,5-Difluoro-2-Nitrophenylboronic Acid
CAS No.	1150114-60-5
Molecular Formula	C6H4BF2NO4
Molecular Weight	202.91 g/mol
Synonyms	2-Nitro-3,5-difluorophenylboronic Acid; (3,5-Difluoro-2-nitrophenyl)boronic Acid; 3,5-Difluoro-2-nitrobenzeneboronic Acid; Boronic acid, B-(3,5-difluoro-2-nitrophenyl)-; 1150114-60-5; 3,5-Difluoro-2-nitrophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-2-Nitrophenylboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry to verify identity, purity, and conformity to customer specifications. Our quality commitment ensures material suitable for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.