Description

5-Amino-2,3-Difluorophenylboronic Acid is a high-value, multifunctional aromatic boronic acid derivative featuring both amino and fluorine substituents. This compound is a critical building block in modern synthetic chemistry, prized for its role in facilitating Suzuki-Miyaura cross-coupling reactions to create complex biaryl structures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in advanced material science for creating functional polymers and organic electronic components.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a monomer or functionalizing agent in the production of advanced polymers, liquid crystals, and organic light-emitting diodes (OLEDs).
• Chemical Research: Employed in academic and industrial R&D for constructing complex molecular architectures via palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: The amino and boronic acid groups make it a useful scaffold for designing novel ligands and organocatalysts.
• Diagnostic Reagent Synthesis: Potential use in creating molecular probes and sensors due to its specific binding affinity with diols (saccharides).

Basic Information

Product Name	5-Amino-2,3-Difluorophenylboronic Acid
CAS No.	1150114-58-1
Molecular Formula	C6H6BF2NO2
Molecular Weight	172.93 g/mol
Synonyms	(5-Amino-2,3-difluorophenyl)boronic acid; 2,3-Difluoro-5-aminophenylboronic acid; 5-Amino-2,3-difluorobenzeneboronic acid; Boronic acid, B-(5-amino-2,3-difluorophenyl)-; 1150114-58-1; 5-Amino-2,3-difluorophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Amino-2,3-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0% (as C6H6BF2NO2)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.