Description

2-Fluoro-5-Hydroxyphenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions essential for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the fluorine and hydroxyl substituents for enhanced bioactivity and stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for constructing complex organic frameworks used in electronic displays and lighting.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific chemical or physical properties, such as improved thermal stability or reactivity.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and sensors for biochemical research and diagnostic applications.
• Academic & Contract Research: Employed in R&D laboratories for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Fluoro-5-Hydroxyphenylboronic Acid
CAS No.	1150114-52-5
Molecular Formula	C6H6BFO3
Molecular Weight	155.92 g/mol
Synonyms	(2-Fluoro-5-hydroxyphenyl)boronic acid; 5-Borono-3-fluorophenol; 2-Fluoro-5-hydroxybenzeneboronic acid; 3-Fluoro-4-hydroxybenzeneboronic acid; B-(2-Fluoro-5-hydroxyphenyl)boronic acid; 1150114-52-5; 2-Fluoro-5-hydroxy phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.