Description

(3,5-Difluoro-2-Hydroxy-Phenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative essential for modern synthetic chemistry. Its primary value lies as a versatile key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging its difluoro-hydroxy substitution pattern.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organoboron catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, sensors, and metal-organic frameworks (MOFs) due to its functional handle for polymerization and complexation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A key raw material for CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects requiring bespoke boronic acid chemistry.

Basic Information

Product Name	(3,5-Difluoro-2-Hydroxy-Phenyl)Boronic Acid
CAS No.	1150114-51-4
Molecular Formula	C6H5BF2O3
Molecular Weight	173.91 g/mol
Synonyms	3,5-Difluoro-2-hydroxybenzeneboronic acid; 2-Hydroxy-3,5-difluorophenylboronic acid; (3,5-Difluoro-2-hydroxyphenyl)boronic acid; B-(3,5-Difluoro-2-hydroxyphenyl)boronic acid; 3,5-Difluoro-2-hydroxybenzeneboronic Acid; (2-Hydroxy-3,5-difluorophenyl)boronic Acid; 3,5-Difluoro-2-hydroxy-phenylboronic acid
EINECS	Contact for details

Quality Control

Our (3,5-Difluoro-2-Hydroxy-Phenyl)Boronic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality commitment aligns with the standards required for GMP intermediates and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.