Description

3-Amino-5-Fluorophenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both an amino and a fluorine substituent, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine moiety for enhanced biological activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, sensors, and metal-organic frameworks (MOFs) due to its boronic acid functionality.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes targeting serine proteases or for carbohydrate sensing.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific functionalized arylboronic acids.

Basic Information

Product Name	3-Amino-5-Fluorophenylboronic Acid
CAS No.	1150114-48-9
Molecular Formula	C6H7BFNO2
Molecular Weight	154.94 g/mol
Synonyms	(3-Amino-5-fluorophenyl)boronic acid; 5-Fluoro-3-aminophenylboronic acid; 3-Amino-5-fluorobenzeneboronic acid; Boronic acid, B-(3-amino-5-fluorophenyl)-; 3-Fluoro-5-aminophenylboronic acid; 3-Fluoro-5-boronylaniline; 1150114-48-9
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) upon request, which include data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.