Description

3-(4-Ethoxycarbonylbutyloxy)-2,4,6-Trifluorophenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a protected ester moiety, enabling precise molecular construction. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in the synthesis of complex fluorinated aromatic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in constructing novel herbicides, fungicides, and insecticides where the trifluorophenyl group imparts desirable biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic acid functionality makes it a versatile partner for palladium-catalyzed carbon-carbon bond formation with aryl halides.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis or as a scaffold for sensor molecules.
• Chemical Biology Probes: Acts as a building block for creating fluorinated probes and tags used in bio-conjugation and imaging studies.

Basic Information

Product Name	3-(4-Ethoxycarbonylbutyloxy)-2,4,6-Trifluorophenylboronic Acid
CAS No.	1150114-31-0
Molecular Formula	C₁₃H₁₆BF₃O₅
Molecular Weight	320.07 g/mol
Synonyms	2,4,6-Trifluoro-3-(4-(ethoxycarbonyl)butoxy)phenylboronic Acid; [3-(4-Ethoxycarbonylbutoxy)-2,4,6-trifluorophenyl]boronic Acid; 3-(4-Carbethoxybutoxy)-2,4,6-trifluorophenylboronic Acid; Ethyl 5-((3-borono-2,4,6-trifluorophenoxy)butanoate; Boronic acid, B-[3-[4-(ethoxycarbonyl)butoxy]-2,4,6-trifluorophenyl]-; CAS 1150114-31-0
EINECS	Contact for details

Quality Control

Our production of 3-(4-Ethoxycarbonylbutyloxy)-2,4,6-Trifluorophenylboronic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.