Description

2,6-Difluoro-3-Nitrophenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents adjacent to the boronic acid group, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, medicinal chemistry, and material science.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Ligand and Catalyst Development: Serves as a building block for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Difluoro-3-Nitrophenylboronic Acid
CAS No.	1150114-28-5
Molecular Formula	C6H4BF2NO4
Molecular Weight	202.91 g/mol
Synonyms	(2,6-Difluoro-3-nitrophenyl)boronic Acid; 2,6-Difluoro-3-nitrobenzeneboronic Acid; Boronic acid, B-(2,6-difluoro-3-nitrophenyl)-; 3-Nitro-2,6-difluorophenylboronic Acid; 1150114-28-5; B-(2,6-Difluoro-3-nitrophenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Nitrophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards required for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.