Description

(1R,2R)-N,n-Bis{2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzyl}Cyclohexane-1,2-Diamine, Min. 97% is a high-purity, chiral bisphosphine-diamine ligand crucial for enabling highly selective catalytic transformations. Its value lies in providing exceptional stereocontrol in asymmetric hydrogenation and other metal-catalyzed reactions, which is essential for producing enantiomerically pure intermediates. This product is primarily needed by research institutions and pharmaceutical manufacturers developing advanced active pharmaceutical ingredients (APIs) and fine chemicals where precise molecular geometry dictates efficacy and safety.

Application

• As a key chiral ligand in asymmetric hydrogenation catalysts for the synthesis of enantiomerically pure pharmaceutical intermediates.
• For the development of transition metal complexes used in C-C and C-X bond-forming reactions in advanced organic synthesis.
• In academic and industrial R&D for exploring novel catalytic pathways and optimizing reaction selectivity.
• For the production of specialty fine chemicals and agrochemicals requiring high enantiomeric excess (ee).
• As a critical component in catalyst screening libraries for process chemistry and method development.

Basic Information

Product Name	(1R,2R)-N,n-Bis{2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzyl}Cyclohexane-1,2-Diamine, Min. 97%
CAS No.	1150113-66-8
Molecular Formula	C58H64N2P2
Molecular Weight	851.10 g/mol
Synonyms	(1R,2R)-N,N-Bis[2-[bis(3,5-dimethylphenyl)phosphino]benzyl]cyclohexane-1,2-diamine; (R,R)-DACH-Phenyl TunePhos; (1R,2R)-Cyclohexanediamine, N,N-bis[2-[bis(3,5-dimethylphenyl)phosphino]benzyl]-; (R,R)-TunePhos DACH Derivative; Chiral Josiphos-type Ligand; (R,R)-Benzyl-TunePhos; Asymmetric Hydrogenation Ligand 1150113-66-8
EINECS	Contact for details

Quality Control

Our (1R,2R)-N,n-Bis{2-[Bis(3,5-Dimethylphenyl)Phosphino]Benzyl}Cyclohexane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity, ensuring it meets the high standards required for catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to prevent oxidation and maintain stability. Keep the container in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Loss on Drying	Max. 0.5%
Residue on Ignition	Max. 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.