Description

3-(4-Bromophenyl)-n-(4-Iodophenyl)-3-Oxopropanamide is a high-purity, halogenated aromatic β-ketoamide building block. This compound is valued for its unique molecular architecture, which serves as a versatile synthon in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Key pharmaceutical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs).
• Versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Precursor for the development of specialty chemicals and functional materials.
• Used in cross-coupling reactions (e.g., Suzuki, Heck) facilitated by its bromo and iodo functional groups.
• Research chemical for exploring new organic synthesis methodologies and catalytic processes.
• Potential intermediate in the development of agrochemicals and dyes.

Basic Information

Product Name	3-(4-Bromophenyl)-n-(4-Iodophenyl)-3-Oxopropanamide
CAS No.	1148041-59-1
Molecular Formula	C15H11BrINO2
Molecular Weight	444.06 g/mol
Synonyms	3-(4-Bromophenyl)-N-(4-iodophenyl)-3-oxopropanamide; 1-(4-Bromophenyl)-3-[(4-iodophenyl)amino]-1,3-propanedione; 3-Oxo-3-(4-bromophenyl)-N-(4-iodophenyl)propanamide; β-Ketoamide derivative; Halogenated propanamide; Aromatic ketoamide building block
EINECS	Contact for details

Quality Control

Our 3-(4-Bromophenyl)-n-(4-Iodophenyl)-3-Oxopropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.