Description

4-Fluoro-3,5-Dimethylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its enhanced stability and solubility compared to the free boronic acid, facilitating efficient handling and reaction control in sensitive processes. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in Suzuki-Miyaura cross-coupling reactions to construct complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated and dimethylated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-3,5-Dimethylphenylboronic Acid, Pinacol Ester
CAS No.	1147894-98-1
Molecular Formula	C14H20BFO2
Molecular Weight	250.12 g/mol
Synonyms	4-Fluoro-3,5-dimethylbenzeneboronic acid pinacol ester; 2-(4-Fluoro-3,5-dimethylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Fluoro-3,5-dimethylphenylboronic acid neopentyl glycol ester (common misnomer); 4-Fluoro-3,5-xylylboronic acid pinacol ester; (4-Fluoro-3,5-dimethylphenyl)boronic acid pinacol ester; B-(4-Fluoro-3,5-dimethylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-Fluoro-3,5-dimethylbenzeneboronic acid MIDA ester (related compound); 1147894-98-1
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3,5-Dimethylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and consistency, meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.