Description

(R)-3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile is a high-purity chiral nitrile building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex, biologically active molecules, offering a defined stereocenter for precise molecular architecture. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, including potential kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the discovery and production of advanced crop protection agents with specific stereochemical requirements.
• Chemical Biology Probe Development: Serves as a building block for creating molecular probes to study enzyme function and biological pathways.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for enantioselective synthesis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.

Basic Information

Item	Details
Product Name	(R)-3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile
CAS No.	1146629-83-5
Molecular Formula	C11H14BrN3
Molecular Weight	268.16 g/mol
Synonyms	(R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; (R)-3-Cyclopentyl-3-(4-bromo-1H-pyrazol-1-yl)propanenitrile; 3-Cyclopentyl-3-(4-bromo-1H-pyrazol-1-yl)propanenitrile, (R)-; (R)-3-(4-Bromopyrazol-1-yl)-3-cyclopentylpropionitrile; 1146629-83-5; (R)-enantiomer of 3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
EINECS	Contact for details

Quality Control

Our (R)-3-(4-Bromo-1H-Pyrazol-1-Yl)-3-Cyclopentylpropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.