Description

tert-Butyl2-(2-Aminoacetamido)Ethylcarbamate is a protected amino acid derivative, specifically a Boc-protected glycine ethylenediamine analog, serving as a crucial building block in organic synthesis. Its primary value lies in providing a versatile, orthogonal protecting group strategy for the synthesis of complex peptides, peptidomimetics, and other bioactive molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in the design and construction of peptidomimetics to improve metabolic stability and bioavailability of drug candidates.
• Linker Chemistry: Serves as a functionalized spacer or linker molecule in bioconjugation and the development of antibody-drug conjugates (ADCs).
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group allows for selective deprotection under mild acidic conditions, enabling complex multi-step syntheses.
• Fine Chemical Synthesis: Intermediate in the custom synthesis of specialty chemicals, catalysts, and ligands for asymmetric synthesis.

Basic Information

Product Name	tert-Butyl2-(2-Aminoacetamido)Ethylcarbamate
CAS No.	1146298-55-6
Molecular Formula	C9H19N3O3
Molecular Weight	217.27 g/mol
Synonyms	Boc-NH-CH2-C(O)-NH-CH2-CH2-NH2; 2-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)amino]-2-oxoacetic acid; Glycine, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, amide; N-(2-Aminoethyl)-N-(tert-butoxycarbonyl)glycinamide; tert-Butyl N-[2-[(2-aminoacetyl)amino]ethyl]carbamate; Boc-EDA-Gly-NH2
EINECS	Contact for details

Quality Control

Our tert-Butyl2-(2-Aminoacetamido)Ethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and cGMP manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.