Description

2-(6-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development programs targeting new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds.
• API Development: Serves as a precursor in the development and scale-up of new active pharmaceutical ingredients.
• Biochemical Research: Potential tool compound for probing biological pathways and enzyme interactions.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry.

Basic Information

Product Name	2-(6-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide
CAS No.	1144489-78-0
Molecular Formula	C₁₄H₁₂ClN₅OS
Molecular Weight	333.80 g/mol
Synonyms	2-(6-Chloro-1H-indol-1-yl)-N-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 2-(6-Chloroindol-1-yl)-N-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide; 1144489-78-0; Acetamide, 2-(6-chloro-1H-indol-1-yl)-N-[(2E)-5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene]-; (2E)-2-(6-Chloro-1H-indol-1-yl)-N-(5-ethyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide
EINECS	Contact for details

Quality Control

Our 2-(6-Chloro-1H-Indol-1-Yl)-n-[(2E)-5-Ethyl-1,3,4-Thiadiazol-2(3H)-Ylidene]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.