Description

1-[(3,5-Dimethyl-1H-Pyrrol-2-Yl)Carbonyl]Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for complex synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of protease inhibitors due to its piperidine-carboxylic acid structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthetic routes.
• Chemical Biology Probes: Utilized in the development of chemical probes for target identification and validation in biological systems.
• Academic Research: A valuable reagent for universities and research institutes exploring new heterocyclic chemistry and pharmacophore design.

Basic Information

Product Name	1-[(3,5-Dimethyl-1H-Pyrrol-2-Yl)Carbonyl]Piperidine-3-Carboxylic Acid
CAS No.	1142209-94-6
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	3-Piperidinecarboxylic acid, 1-[(3,5-dimethyl-1H-pyrrol-2-yl)carbonyl]-; 1-(3,5-Dimethyl-1H-pyrrole-2-carbonyl)piperidine-3-carboxylic acid; 3-Carboxy-1-(3,5-dimethylpyrrole-2-carbonyl)piperidine; 1-(3,5-Dimethyl-1H-pyrrol-2-yl)(oxo)methyl]piperidine-3-carboxylic acid; 1142209-94-6; 1-(3,5-Dimethylpyrrole-2-carbonyl)nipecotic acid; Nipecotic acid, 1-(3,5-dimethylpyrrole-2-carbonyl)-
EINECS	Contact for details

Quality Control

Our 1-[(3,5-Dimethyl-1H-Pyrrol-2-Yl)Carbonyl]Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.