Description

Intermedin-53 (Human) is a synthetic peptide fragment corresponding to the human adrenomedullin 2 (ADM2) protein, a member of the calcitonin gene-related peptide family. This high-purity reference standard is critical for advancing research into cardiovascular regulation, metabolic processes, and tumor biology. It is an essential reagent for pharmaceutical R&D, academic research, and diagnostic assay development, providing a reliable tool for bioactivity studies and analytical method validation.

Application

• Biomedical Research: Used as a reference standard in studies investigating the physiological and pathophysiological roles of adrenomedullin 2 in cardiovascular function, renal regulation, and energy metabolism.
• Drug Discovery & Development: Serves as a critical tool for screening, characterizing, and validating potential therapeutic agents targeting the ADM2 receptor pathway.
• Diagnostic Assay Development: Employed as a calibrator or control in the development of immunoassays (e.g., ELISA) for quantifying ADM2 levels in biological samples.
• Cell Signaling Studies: Applied in in vitro cell culture models to study receptor binding, signal transduction mechanisms, and downstream cellular responses.
• Quality Control: Functions as an analytical standard for purity and identity confirmation in peptide manufacturing and quality assurance laboratories.

Basic Information

Product Name	Intermedin-53 (Human)
CAS No.	1140977-96-3
Molecular Formula	C264H419N77O78S2
Molecular Weight	5797.8 g/mol
Synonyms	Adrenomedullin 2 (1-53), human; ADM2 (1-53); Intermedin (1-53); hIMD (1-53); AM2 (1-53); hADM2 (1-53); Peptide Fragment 1-53 of Adrenomedullin 2; hIMD-53
EINECS	Contact for details

Quality Control

Every batch of Intermedin-53 (Human) is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products are tested to ensure compliance with high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA), providing data on purity (HPLC), molecular weight confirmation (MS), and peptide content, is supplied with each shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Molecular Weight	5797.8 ± 2.0 Da (MALDI-TOF MS)
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.