Description

Benzene, 1-Ethynyl-2,3,4-Trimethoxy- is a specialized aromatic building block featuring a unique combination of an ethynyl group and multiple methoxy substituents. This compound is valued for its role as a key intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in coupling reactions (e.g., Sonogashira) to introduce acetylene functionality into target molecules.
• Material Science Research: Serves as a monomer or precursor for developing novel polymers and advanced organic materials.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and herbicides.
• Ligand and Catalyst Synthesis: Used to create sophisticated ligands for metal-catalyzed reactions and organometallic chemistry.
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in both university laboratories and corporate R&D centers.

Basic Information

Product Name	Benzene, 1-Ethynyl-2,3,4-Trimethoxy-
CAS No.	1140509-00-7
Molecular Formula	C₁₁H₁₀O₃
Molecular Weight	190.20 g/mol
Synonyms	1-Ethynyl-2,3,4-trimethoxybenzene; 2,3,4-Trimethoxyphenylacetylene; (2,3,4-Trimethoxyphenyl)ethyne; 2,3,4-Trimethoxybenzeneacetylene; Trimethoxyphenylacetylene; Ethynyltrimethoxybenzene; 1-Ethynyl-2,3,4-trimethoxy-benzene
EINECS	Contact for details

Quality Control

Our Benzene, 1-Ethynyl-2,3,4-Trimethoxy- is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.