Description

4-Acetyl-2-Methylbenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both acetyl and nitrile functional groups on a methyl-substituted benzene ring, makes it a valuable intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules with benzonitrile or acetophenone cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where its structure can be modified to enhance biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Dye and Pigment Intermediate: Potential starting material for the synthesis of complex colorants and functional dyes.

Basic Information

Product Name	4-Acetyl-2-Methylbenzonitrile
CAS No.	1138444-80-0
Molecular Formula	C10H9NO
Molecular Weight	159.18 g/mol
Synonyms	2-Methyl-4-acetylbenzonitrile; 1-(4-Cyano-3-methylphenyl)ethanone; 4-Acetyl-o-tolunitrile; 2-Methyl-4-cyanobenzophenone; 4-Cyano-3-methylacetophenone; p-Acetyl-o-tolunitrile; Ethanone, 1-(4-cyano-3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 4-Acetyl-2-Methylbenzonitrile is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data with each shipment, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. Certificates of Analysis (COA) detailing all relevant specifications are available upon request and are aligned with standard industry practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.