Description

Ethyl 2-{[(4-Fluorophenyl)Methyl]Amino}Acetate Hydrochloride is a high-purity organic salt compound, primarily valued as a critical pharmaceutical intermediate. Its molecular structure, featuring a fluorinated aromatic ring and an ester-protected amino acid derivative, makes it a versatile building block for medicinal chemistry research and development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Intermediate in the development of advanced pesticides and herbicides, leveraging the fluorophenyl moiety.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or probes used in biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	Ethyl 2-{[(4-Fluorophenyl)Methyl]Amino}Acetate Hydrochloride
CAS No.	1135028-80-6
Molecular Formula	C12H17ClFNO2
Molecular Weight	261.72 g/mol
Synonyms	Ethyl N-[(4-Fluorophenyl)methyl]glycinate Hydrochloride; 2-[[(4-Fluorophenyl)methyl]amino]acetic acid ethyl ester hydrochloride; Ethyl 2-((4-Fluorobenzyl)amino)acetate HCl; 4-Fluorobenzylamino-acetic acid ethyl ester hydrochloride; N-(4-Fluorobenzyl)glycine ethyl ester hydrochloride; Ethyl (4-fluorobenzyl)glycinate hydrochloride; Glycine, N-[(4-fluorophenyl)methyl]-, ethyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 2-{[(4-Fluorophenyl)Methyl]Amino}Acetate Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.