Description

(1E,4Z,6E)-1,7-Bis[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one is a sophisticated, high-purity synthetic intermediate characterized by its unique conjugated heptatrienone structure protected with tert-butyldimethylsilyl (TBDMS) groups. This compound matters as a critical building block in advanced organic synthesis, offering precise control over molecular architecture for the development of novel chemical entities. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products, bioactive molecules, and materials science research, where its protected phenolic functionalities are essential for selective chemical transformations.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates and pharmacologically active molecules.
• Natural Product Synthesis: Used in the total or semi-synthesis of natural products with polyphenolic or curcuminoid-related frameworks.
• Chemical Biology Research: Employed as a probe or building block for studying biological pathways and protein interactions.
• Advanced Material Development: Acts as a monomer or cross-linking agent in the creation of specialized polymers with unique optical or electronic properties.
• Organic Synthesis Research: Utilized in methodological studies for developing new reactions involving protected phenols and conjugated enones.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related synthetic processes.

Basic Information

Product Name	(1E,4Z,6E)-1,7-Bis[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
CAS No.	1134639-23-8
Molecular Formula	C35H52O6Si2
Molecular Weight	624.96 g/mol
Synonyms	5-Hydroxy-1,7-bis(4-((tert-butyldimethylsilyl)oxy)-3-methoxyphenyl)hepta-1,4,6-trien-3-one; Bis-TBDMS Protected Curcumin Derivative; TBDMS-Curcumin Derivative; 1,7-Bis(4-(tert-butyldimethylsilyloxy)-3-methoxyphenyl)-5-hydroxy-1,4,6-heptatrien-3-one; (1E,4Z,6E)-5-Hydroxy-1,7-bis[4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl]hepta-1,4,6-trien-3-one; Silyl Ether Derivative of Curcumin Analog
EINECS	Contact for details

Quality Control

Our (1E,4Z,6E)-1,7-Bis[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and structural integrity, with specifications typically meeting or exceeding 95% purity by HPLC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C for long-term stability. This compound is light-sensitive and may be hygroscopic; allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.