Description

Galnac Beta(1-3)Gal Alpha(1-4)Gal Beta(1-4)Glc-β-Pnp is a high-purity, synthetic tetrasaccharide derivative, specifically designed as a critical biochemical tool. This compound serves as a highly specific substrate and inhibitor for studying glycosyltransferase and glycosidase enzymes involved in complex carbohydrate biosynthesis. It is essential for researchers and developers in glycobiology, enzymology, and pharmaceutical discovery, particularly for investigating metabolic pathways, developing diagnostic assays, and screening for novel therapeutic agents.

Application

• Enzyme Substrate for Glycosyltransferases: Used in kinetic studies and activity assays for enzymes like β-1,3-galactosyltransferases and α-1,4-galactosyltransferases.
• Glycosidase Inhibition Studies: Acts as a competitive inhibitor or mechanistic probe for enzymes that cleave GalNAc, Gal, or Glc linkages.
• Glycoconjugate Synthesis: Serves as a key building block or acceptor molecule in the chemoenzymatic synthesis of complex oligosaccharides and glycoconjugates.
• Biochemical Research & Diagnostic Development: Employed in research to understand carbohydrate-mediated biological recognition, cell signaling, and for developing diagnostic tools for glycosylation-related disorders.
• Pharmaceutical Screening: Utilized in high-throughput screening (HTS) campaigns to identify potential drug candidates that modulate glycosylation enzyme activity.
• Standards and Controls: Functions as a certified reference standard for analytical methods like HPLC and LC-MS in quality control and metabolic pathway analysis.

Basic Information

Product Name	Galnac Beta(1-3)Gal Alpha(1-4)Gal Beta(1-4)Glc-β-Pnp
CAS No.	1134635-03-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GalNAcβ1-3Galα1-4Galβ1-4Glcβ-PNP; p-Nitrophenyl β-lactoside derivative with GalNAc and Gal extensions; Tetrasaccharide-PNP conjugate; GalNAc(β1-3)Gal(α1-4)Gal(β1-4)Glc(β)-p-nitrophenyl; Glycosidase substrate 1134635-03-2; Synthetic oligosaccharide acceptor; PNP-tagged tetrasaccharide; N-Acetylgalactosamine-containing glycosyl acceptor.
EINECS	Contact for details

Quality Control

Our Galnac Beta(1-3)Gal Alpha(1-4)Gal Beta(1-4)Glc-β-Pnp is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98% (on dried basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; partially soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.