Description

tert-Butyl (4-Oxo-4-(Pyridin-3-Yl)Butyl)Carbamate is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key synthon in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery pipelines. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of potential drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material for custom synthesis projects and scale-up processes under GMP or non-GMP conditions.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group is utilized for the temporary protection of amines during complex synthetic sequences.
• Chemical Biology Probes: Can be incorporated into the design of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	tert-Butyl (4-Oxo-4-(Pyridin-3-Yl)Butyl)Carbamate
CAS No.	1134327-87-9
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	1-Boc-4-(3-pyridyl)-4-oxobutylamine; tert-Butyl N-[4-oxo-4-(pyridin-3-yl)butyl]carbamate; 3-Pyridinebutanamide, N-[(1,1-dimethylethoxy)carbonyl]-; 4-(3-Pyridinyl)-4-oxo-1-butanesulfonamide, N-Boc-protected; Boc-4-(3-pyridoyl)butylamine; N-Boc-4-(3-Pyridyl)-4-oxobutylamine; (4-Oxo-4-pyridin-3-yl-butyl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Oxo-4-(Pyridin-3-Yl)Butyl)Carbamate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.