Description

Ropinirole-D7 Hydrochloride is a high-purity, deuterium-labeled internal standard essential for precise quantitative analysis in pharmaceutical research and development. This stable isotope-labeled compound is critical for ensuring accuracy and reliability in bioanalytical methods, particularly liquid chromatography-mass spectrometry (LC-MS). It is primarily utilized by analytical chemists and researchers in pharmaceutical companies, contract research organizations (CROs), and academic institutions for pharmacokinetic studies, drug metabolism research, and quality control of the active pharmaceutical ingredient ropinirole.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a quantitative reference standard in the bioanalysis of ropinirole in biological matrices such as plasma, serum, and urine.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Method Development and Validation: Serves as a critical component in developing and validating robust, GLP-compliant analytical methods.
• Impurity Profiling and Characterization: Aids in the identification and quantification of related substances and degradants in drug substance and product testing.
• Doping Control Analysis: Applied in sports anti-doping laboratories for the precise detection of ropinirole.

Basic Information

Product Name	Ropinirole-D7 Hydrochloride
CAS No.	1132746-04-3
Molecular Formula	C16H17D7N3O•HCl
Molecular Weight	313.88 g/mol
Synonyms	4-[2-(Dipropyl-d7-amino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride; Ropinirole-d7 HCl; 4-[2-(N,N-Dipropyl-d7-amino)ethyl]-2-indolinone hydrochloride; SKF-101468-d7 hydrochloride; ReQuip-d7 hydrochloride; (±)-Ropinirole-d7 hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Ropinirole-D7 Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical and isotopic purity to meet the exacting standards of modern bioanalytical laboratories. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (by HPLC), isotopic enrichment, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98.0 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.