Description

3,5-Difluoro-4-Hydroxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its role as a key building block in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used to create novel herbicides and fungicides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials used in displays and lighting.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific thermal or chemical resistance properties.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and sensors for biochemical research.
• Catalyst Ligand Synthesis: Employed in the preparation of sophisticated ligands for asymmetric catalysis.

Basic Information

Product Name	3,5-Difluoro-4-Hydroxyphenylboronic Acid
CAS No.	1132666-81-9
Molecular Formula	C6H5BF2O3
Molecular Weight	173.92 g/mol
Synonyms	(3,5-Difluoro-4-hydroxyphenyl)boronic acid; 4-Borono-2,6-difluorophenol; 2,6-Difluoro-4-boronophenol; B-(3,5-Difluoro-4-hydroxyphenyl)boronic acid; 3,5-Difluoro-4-hydroxybenzeneboronic acid; DFHPBA; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Hydroxyphenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. Our quality commitment includes comprehensive identity, purity, and impurity profile verification using techniques such as HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.