Description

Arbidol o-Glucuronide is a key metabolite and reference standard of the broad-spectrum antiviral drug Umifenovir (Arbidol). This compound is essential for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and bioanalytical method validation. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the development and quality control of antiviral therapeutics.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quantitative and qualitative analysis of Arbidol and its metabolites in biological matrices.
• Metabolite Identification & Pharmacokinetic Studies: Used in ADME (Absorption, Distribution, Metabolism, Excretion) research to understand the metabolic pathways and clearance mechanisms of Umifenovir.
• Bioanalytical Method Development: Essential for developing and validating sensitive HPLC, LC-MS, or LC-MS/MS assays for drug monitoring in plasma, serum, or urine.
• Drug Impurity Profiling: Acts as a specified impurity standard to ensure the purity and safety of the active pharmaceutical ingredient (API) during manufacturing.
• Preclinical and Clinical Research: Supports toxicology studies and clinical trials by enabling accurate measurement of drug and metabolite levels.
• Quality Control & Assurance: Employed in GMP/GLP environments to verify the identity and purity of batches in pharmaceutical production.

Basic Information

Product Name	Arbidol o-Glucuronide
CAS No.	1130900-96-7
Molecular Formula	C29H39BrN2O8
Molecular Weight	623.54 g/mol
Synonyms	Umifenovir o-Glucuronide; Arbidol Glucuronide; Arbidol Metabolite; Ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate glucuronide; UNII-9V8V3E8ZR2; 1-Methyl-2-((phenylthio)methyl)-3-carbethoxy-4-(dimethylaminomethyl)-5-hydroxy-6-bromoindole glucuronide
EINECS	Contact for details

Quality Control

Our Arbidol o-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and analytical results is provided with every shipment to ensure compliance with research and pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.