Description

2-Bromo-6-Morpholinobenzonitrile is a high-value, multi-functional chemical building block featuring a bromine substituent and a morpholine ring. This compound is essential for facilitating advanced cross-coupling reactions and serving as a key precursor in complex organic syntheses. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to form new carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology & Proteomics: Utilized as a versatile scaffold or labeling agent in the design of molecular probes and enzyme inhibitors.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Bromo-6-Morpholinobenzonitrile
CAS No.	1129540-65-3
Molecular Formula	C11H11BrN2O
Molecular Weight	267.12 g/mol
Synonyms	2-Bromo-6-morpholinobenzonitrile; Benzonitrile, 2-bromo-6-morpholino-; 6-Morpholino-2-bromobenzonitrile; 2-Bromo-6-(morpholin-4-yl)benzonitrile; 2-Bromo-6-(4-morpholinyl)benzonitrile; 1129540-65-3; 2-Bromo-6-morpholin-4-yl-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Morpholinobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.