Description

4-(Pentafluorosulfur)Benzyl Bromide is a high-value organofluorine building block characterized by its reactive benzyl bromide group and unique pentafluorosulfur (SF5) substituent. This compound matters for its role in introducing the highly lipophilic and metabolically stable SF5 group into target molecules, a strategy increasingly used to fine-tune the properties of advanced materials and pharmaceuticals. It is primarily needed by researchers and process chemists in agrochemical, pharmaceutical, and specialty materials development who require reliable, high-purity intermediates for synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly where the introduction of the SF5 group can enhance metabolic stability, lipophilicity, and binding affinity.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and insecticides, where the SF5 moiety can improve biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty materials for electronic displays and organic light-emitting diodes, leveraging the electronic properties of the SF5 group.
• Ligand & Catalyst Development: Employed in the synthesis of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorinated Polymer Chemistry: Acts as a monomer or modifier in the production of high-performance polymers with enhanced chemical and thermal resistance.
• Radiochemistry & Tracer Synthesis: Useful for incorporating fluorine-rich motifs into compounds used in positron emission tomography (PET) and other imaging applications.

Basic Information

Product Name	4-(Pentafluorosulfur)Benzyl Bromide
CAS No.	1126969-29-6
Molecular Formula	C7H4BrF5S
Molecular Weight	295.07 g/mol
Synonyms	α-Bromo-4-(pentafluoro-λ6-sulfanyl)toluene; (4-(Pentafluorosulfanyl)phenyl)methyl Bromide; 4-(SF5)Benzyl Bromide; p-SF5 Benzyl Bromide; 1-(Bromomethyl)-4-(pentafluoro-λ6-sulfanyl)benzene; 4-(Pentafluorosulfur)Benzyl Bromide; 4-(SF5)C6H4CH2Br
EINECS	Contact for details

Quality Control

Our 4-(Pentafluorosulfur)Benzyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can provide material to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.