Description

Eletriptan-D5 CAS NO 1126745-65-0 is a deuterated internal standard of the selective serotonin receptor agonist, eletriptan, specifically designed for analytical applications. This high-purity, isotopically labeled compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry analyses. It is an essential tool for pharmaceutical research and development, quality control laboratories, and forensic toxicology studies requiring precise measurement of eletriptan.

Application

• Quantitative Bioanalysis: Serves as a stable isotope-labeled internal standard for the accurate LC-MS/MS quantification of eletriptan in biological matrices such as plasma, serum, and urine.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in clinical and preclinical research.
• Pharmaceutical Quality Control (QC): Used in assay development and validation to ensure the potency and purity of eletriptan active pharmaceutical ingredient (API) and finished dosage forms.
• Forensic and Clinical Toxicology: Facilitates the reliable identification and quantification of eletriptan in cases of overdose or therapeutic drug monitoring.
• Metabolite Identification: Aids in the structural elucidation of eletriptan metabolites by providing a mass spectrometric reference point.
• Method Development and Validation: Critical for developing robust, sensitive, and specific analytical methods compliant with regulatory guidelines (e.g., FDA, ICH).

Basic Information

Item	Details
Product Name	Eletriptan-D5
CAS No.	1126745-65-0
Molecular Formula	C22H21D5N2O2S
Molecular Weight	383.55 g/mol (approx.)
Synonyms	(3-((1-Methyl-2-pyrrolidinyl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole-2,3,4,5,6-D5); Eletriptan-d5; Eletriptan (phenyl-d5); UK-116,044-d5; Relpax-d5 (deuterated analog)
EINECS	Contact for details

Quality Control

Every batch of Eletriptan-D5 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, typically ≥98% (chemical purity) and ≥99% atom D, confirmed by advanced analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (H-NMR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms (M+5 pattern)
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 99.0%
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.