Description

4-Chloro-2-Fluoro-3-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound matters as a critical building block in modern organic synthesis, particularly for the construction of complex molecules via cross-coupling reactions. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing complex biaryl or heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific halogenated aromatic structures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects and scale-up campaigns.
• Academic & Institutional Research: Utilized in university and government laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1126321-06-9
Molecular Formula	C13H17BClFO3
Molecular Weight	286.53 g/mol
Synonyms	4-Chloro-2-fluoro-3-methoxyphenylboronic acid pinacol ester; (4-Chloro-2-fluoro-3-methoxyphenyl)boronic acid pinacol ester; 2-(4-Chloro-2-fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-2-fluoro-3-methoxybenzeneboronic acid pinacol ester; Pinacol (4-chloro-2-fluoro-3-methoxyphenyl)boronate; Boronic acid, B-(4-chloro-2-fluoro-3-methoxyphenyl)-, 1,1-dimethylethyl ester (9CI); CAS 1126321-06-9
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluoro-3-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.