Description

4-(Boc-Amino)-4-Methyl-1-Pentanol is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in the Boc (tert-butoxycarbonyl) protecting group, which safeguards the amine functionality during multi-step reactions, enabling the precise construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Peptide Mimetics & PROTACs: Used in the construction of peptide analogs and Proteolysis Targeting Chimeras (PROTACs) due to its bifunctional (amine & alcohol) and sterically hindered structure.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Incorporation into specialty polymers to impart specific functional groups or chiral centers for advanced material properties.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	4-(Boc-Amino)-4-Methyl-1-Pentanol
CAS No.	1123693-87-7
Molecular Formula	C11H23NO3
Molecular Weight	217.31 g/mol
Synonyms	4-Methyl-4-[(tert-butoxycarbonyl)amino]-1-pentanol; 1-Pentanol, 4-[(1,1-dimethylethoxy)carbonyl]amino]-4-methyl-; 4-(N-Boc-amino)-4-methylpentan-1-ol; N-Boc-4-amino-4-methyl-1-pentanol; tert-Butyl (4-hydroxy-1,1-dimethylbutyl)carbamate; Boc-Amp-ol; (4-Hydroxy-1,1-dimethylbutyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(Boc-Amino)-4-Methyl-1-Pentanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.