Description

Clindamycin Palmitate Sulfoxide is a key pharmaceutical intermediate and derivative of the lincosamide antibiotic clindamycin. This compound is of significant value in the research and development of novel antibacterial agents and in the synthesis of high-purity reference standards. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for advanced drug development and analytical applications.

Application

• Pharmaceutical Intermediate: Critical raw material in the synthesis of advanced clindamycin derivatives and prodrugs.
• Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control and regulatory testing.
• Antibacterial Research: Serves as a precursor or model compound in microbiological and pharmacological studies to explore new mechanisms of action.
• Process Chemistry: Employed in scale-up and optimization of manufacturing processes for related antibiotic compounds.
• Impurity Profiling: Essential for identifying and quantifying related substances in clindamycin palmitate hydrochloride drug substance and finished products.

Basic Information

Product Name	Clindamycin Palmitate Sulfoxide
CAS No.	1123211-65-3
Molecular Formula	C34H65ClN2O6S
Molecular Weight	665.41 g/mol
Synonyms	Clindamycin Palmitate S-Oxide; (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfinyl)oxan-2-yl]propyl]-1-methyl-4-propyl-N-[(2S,3R,4S,5S)-3,4,5-tris(palmitoyloxy)oxan-2-yl]pyrrolidine-2-carboxamide; Clindamycin Palmitate Sulfoxide Derivative; Antibiotic L 12649 Sulfoxide Ester
EINECS	Contact for details

Quality Control

Our Clindamycin Palmitate Sulfoxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference materials. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for assay, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.