Description

3,5-Difluorophenyltert-Butylether is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its value lies in the unique electronic and steric properties imparted by the difluoro and tert-butoxy substituents, which are critical for modulating the reactivity and physical characteristics of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of novel fluorinated polymers and liquid crystals with tailored thermal and optical properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes due to the stability of the ether linkage.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated aromatic architectures.

Basic Information

Product Name	3,5-Difluorophenyltert-Butylether
CAS No.	1121586-36-4
Molecular Formula	C10H12F2O
Molecular Weight	186.20 g/mol
Synonyms	1-tert-Butoxy-3,5-difluorobenzene; 3,5-Difluorophenyl tert-butyl ether; tert-Butyl 3,5-difluorophenyl ether; 3,5-Difluoro-1-(tert-butoxy)benzene; 3,5-Difluorophenol tert-butyl ether; 2-Methyl-2-(3,5-difluorophenoxy)propane; (3,5-Difluorophenoxy)(tert-butyl); DFBE (abbreviation)
EINECS	Contact for details

Quality Control

Our 3,5-Difluorophenyltert-Butylether is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.