Description

3-Bromo-5-Isopropoxy-Benzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique benzonitrile core, substituted with bromine and an isopropoxy group, makes it a critical precursor for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where its specific substitution pattern can tune material properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	3-Bromo-5-Isopropoxy-Benzonitrile
CAS No.	1119779-02-0
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	5-Isopropoxy-3-bromobenzonitrile; 3-Bromo-5-(1-methylethoxy)benzonitrile; Benzonitrile, 3-bromo-5-(1-methylethoxy)-; 3-Bromo-5-isopropoxybenzonitrile; 3-Bromo-5-(propan-2-yloxy)benzonitrile; 1119779-02-0; 3-Br-5-iPrO-BnCN
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Isopropoxy-Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, and can support development and commercial projects requiring ICH stability data, residual solvent analysis, and compliance with REACH regulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.