Description

tert-Butyl 4-Cyano-4-Pyrrolidin-1-Ylpiperidine-1-Carboxylate (Saltdata: Free) is a high-value, multi-functional piperidine derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in its versatile molecular scaffold, which is designed for efficient incorporation into complex target molecules, particularly in pharmaceutical research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-purity intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Scaffold: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Process Chemistry: Employed in the scale-up and route development for the commercial manufacturing of novel therapeutic agents.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and pesticides.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 4-Cyano-4-Pyrrolidin-1-Ylpiperidine-1-Carboxylate (Saltdata: Free)
CAS No.	1119452-74-2
Molecular Formula	C15H25N3O2
Molecular Weight	279.38 g/mol
Synonyms	1-Boc-4-Cyano-4-(pyrrolidin-1-yl)piperidine; 4-Cyano-4-(pyrrolidin-1-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyano-4-(1-pyrrolidinyl)-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-cyano-4-(1-pyrrolidinyl)-, 1,1-dimethylethyl ester; 4-Cyano-4-(pyrrolidin-1-yl)piperidine-1-Boc; 1-Boc-4-cyano-4-pyrrolidinopiperidine; 4-(Pyrrolidin-1-yl)-4-cyanopiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyano-4-Pyrrolidin-1-Ylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.