Description

n-Boc-(2-Amino-3-Methylbutyl)Amine is a protected diamine derivative, specifically a tert-butyloxycarbonyl (Boc)-protected aminoalkylamine. This compound is a crucial chiral building block in organic synthesis, valued for its role in constructing complex molecular architectures with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Chemistry: Serves as a backbone or side-chain component in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability.
• Ligand and Catalyst Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRAM) for producing high-value, bespoke organic molecules.
• Bioconjugation and Linker Chemistry: Functions as a spacer or functional handle in bioconjugation strategies for antibody-drug conjugates (ADCs) or probes.

Basic Information

Product Name	n-Boc-(2-Amino-3-Methylbutyl)Amine
CAS No.	1117693-61-4
Molecular Formula	C10H22N2O2
Molecular Weight	202.30 g/mol
Synonyms	tert-Butyl N-[(2S)-1-amino-3-methylbutan-2-yl]carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutan-1-amine; Boc-L-valinol; N-Boc-1,2-diamino-3-methylbutane; 1-Amino-3-methyl-2-[(tert-butoxycarbonyl)amino]butane; N-α-Boc-L-2,3-diaminobutanoic acid amide derivative; Boc-protected valine-derived diamine
EINECS	Contact for details

Quality Control

Our n-Boc-(2-Amino-3-Methylbutyl)Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.