Description

2,3-Difluoro-4-Methylphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex, fluorinated drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that benefit from the unique properties of the difluoromethylphenyl moiety.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating fluorinated aromatic cores in advanced electronic and display materials.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and constructing molecular libraries.

Basic Information

Product Name	2,3-Difluoro-4-Methylphenylboronic Acid Pinacol Ester
CAS No.	1116681-99-2
Molecular Formula	C₁₄H₁₉BF₂O₂
Molecular Weight	268.11 g/mol
Synonyms	2,3-Difluoro-4-methylbenzeneboronic acid pinacol ester; (2,3-Difluoro-4-methylphenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2,3-difluoro-4-methylphenyl)-1,3,2-dioxaborolane; 2-(2,3-Difluoro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2,3-difluoro-4-methylphenyl)boronate; Boronic acid, B-(2,3-difluoro-4-methylphenyl)-, 1,1-dimethylethyl ester; 2,3-Difluoro-p-tolylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methylphenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.