Description

(4-Bromo-2-Chloro-6-Fluorophenyl)Boronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound matters as a critical intermediate in modern cross-coupling reactions, enabling the precise construction of complex molecules for advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and advanced materials chemists for applications in drug discovery, catalyst development, and the synthesis of novel functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, essential for constructing biaryl and heterobiaryl scaffolds in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly for creating complex, halogenated aromatic structures with potential biological activity.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Useful for creating novel boron-containing ligands for metal complexes used in catalysis.
• Chemical Biology Probes: Can be utilized to synthesize molecular probes for studying biological processes and target identification.

Basic Information

Product Name	(4-Bromo-2-Chloro-6-Fluorophenyl)Boronic Acid Pinacol Ester
CAS No.	1111096-22-0
Molecular Formula	C₁₂H₁₄BBrClFO₂
Molecular Weight	335.41 g/mol
Synonyms	4-Bromo-2-chloro-6-fluorobenzeneboronic acid pinacol ester; (4-Bromo-2-chloro-6-fluorophenyl)boronic acid pinacol ester; 2-(4-Bromo-2-chloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-2-chloro-6-fluorophenylboronic acid pinacol ester; Pinacol (4-bromo-2-chloro-6-fluorophenyl)boronate; B-(4-Bromo-2-chloro-6-fluorophenyl)boronic acid pinacol ester; CAS 1111096-22-0
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Chloro-6-Fluorophenyl)Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.