Description

2,6-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require the incorporation of difluoromethoxy-substituted aromatic systems.
• Liquid Crystal & OLED Material Production: Enables the synthesis of advanced organic electronic materials, where the pinacol ester group offers enhanced stability and solubility for precise molecular assembly.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the creation of specialty polymers with tailored optical or electronic properties.
• Chemical Research & Development: Employed in academic and industrial labs for methodological development and the exploration of new chemical spaces in organoboron chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scale-up projects.

Basic Information

Product Name	2,6-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester
CAS No.	1111096-19-5
Molecular Formula	C14H19BF2O3
Molecular Weight	284.11 g/mol
Synonyms	2,6-Difluoro-4-methoxyphenylboronic acid pinacol ester; 4-Methoxy-2,6-difluorophenylboronic acid pinacol ester; (2,6-Difluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2,6-Difluoro-4-methoxybenzeneboronic acid pinacol ester; Pinacol (2,6-difluoro-4-methoxyphenyl)boronate; CAS 1111096-19-5
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Methoxyphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.