Description

Lusutrombopag is a potent, orally bioavailable, small-molecule thrombopoietin receptor agonist. This compound is critical for the treatment of thrombocytopenia in adult patients with chronic liver disease who are scheduled to undergo a procedure, as it stimulates platelet production to reduce the risk of bleeding. It is an essential active pharmaceutical ingredient (API) for pharmaceutical manufacturers developing targeted hematology and hepatology therapeutics. The product is supplied as Lusutrombopag CAS NO 1110768-00-7, meeting the stringent quality standards required for drug substance synthesis.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of prescription medications.
• Manufacturing of finished dosage forms, primarily oral tablets, for the treatment of thrombocytopenia.
• Clinical research and development of novel therapies for platelet disorders.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Process development and scale-up activities for generic and innovative drug manufacturers.
• Biochemical research focusing on thrombopoietin receptor signaling pathways and megakaryocyte differentiation.

Basic Information

Product Name	Lusutrombopag
CAS No.	1110768-00-7
Molecular Formula	C29H34Cl2N4O5S2
Molecular Weight	645.64 g/mol
Synonyms	Mulpleta (Brand Name); S-888711; 1-[3-Chloro-5-({[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)-1,3-thiazol-2-yl]carbamoyl}amino)-2-hydroxypropyl]piperidine-4-carboxylic acid; Lusutrombopagum; TPO Receptor Agonist S-888711
EINECS	Contact for details

Quality Control

Our Lusutrombopag is manufactured under strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets or exceeds pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability, purity, and consistency for your critical manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.