Description

1-Cyanocyclopropane-1-Sulfonamide is a high-purity, specialized organic building block featuring a unique cyclopropane ring functionalized with both cyano and sulfonamide groups. This compound is valued for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the constrained, three-membered ring structure into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the cyclopropane moiety can enhance biological activity and stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways, leveraging the reactive cyano and sulfonamide groups.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers and functional materials with specific thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific sulfonamide derivative.

Basic Information

Product Name	1-Cyanocyclopropane-1-Sulfonamide
CAS No.	1108658-23-6
Molecular Formula	C4H6N2O2S
Molecular Weight	146.17 g/mol
Synonyms	Cyclopropanesulfonamide, 1-cyano-; 1-Cyano-1-sulfamoylcyclopropane; 1-Cyanocyclopropanesulfonamide; 1-Sulfamoyl-1-cyanocyclopropane; Cyclopropane-1-sulfonamide, 1-cyano-; 1-Cyano-cyclopropane-1-sulfonic acid amide
EINECS	Contact for details

Quality Control

Our 1-Cyanocyclopropane-1-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.